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Choosing the Right LLM: OpenAI vs Anthropic vs Open Source for Production

A practical guide to selecting LLMs for production AI platforms. Compare GPT-5, Claude Opus 4.6, Llama 4, and more across cost, latency, and capability.

Choosing the Right LLM: OpenAI vs Anthropic vs Open Source for Production
Matt Owens
Matt Owens
1 Dec 2025 - 3 min read

Choosing the Right LLM: OpenAI vs Anthropic vs Open Source

After integrating dozens of LLMs into production platforms, we’ve developed clear opinions on when to use each provider. This guide covers the practical tradeoffs-not benchmarks, but real-world production considerations.

Bottom line: Most production platforms should use multiple models. Use expensive models for complex reasoning, cheap models for simple tasks, and open source for cost-sensitive or privacy-critical workloads.


The current landscape (December 2025)

Closed-source leaders

ProviderTop ModelBest ForCost (per 1M tokens)
OpenAIGPT-5General purpose, function calling$1.25 input / $10 output
OpenAIGPT-5 miniCost-sensitive, simple tasks$0.25 input / $2 output
OpenAIo3Complex reasoning, multi-step logic$1 input / $4 output (Flex)
AnthropicClaude Opus 4.6Complex reasoning, extended thinking$5 input / $25 output
AnthropicClaude Sonnet 4.5Balanced quality and cost$3 input / $15 output
AnthropicClaude Haiku 4.5Fast, cheap, high volume$1 input / $5 output
GoogleGemini 3 ProLong context, multimodal$2 input / $12 output
GoogleGemini 3 FlashFast, cheap, 90% cache savings$0.50 input / $3 output

Open source options

ModelArchitectureBest ForNotes
Llama 4 Scout109B total (17B active, MoE)General purpose, 10M contextRuns on single H100 with Int4
Llama 4 Maverick400B total (17B active, 128 experts)Quality-focused, 1M contextCodistilled from Behemoth
Mistral Large123BEuropean compliance, multilingualStrong GDPR story
DeepSeek R1MoEReasoning, cost-effectiveOpen weights reasoning model

How to choose: decision framework

1. What’s the primary task?

Complex reasoning, analysis, or writing:

  • Claude Opus 4.6 with extended thinking for best quality
  • o3 for multi-step reasoning and planning
  • GPT-5 mini for simpler reasoning at lower cost

Classification, extraction, or simple Q&A:

  • Gemini 3 Flash (fastest closed-source at $0.50/$3)
  • GPT-5 mini for balance of speed and quality
  • Llama 4 Scout (self-hosted for volume)

Long document processing (50K+ tokens):

  • Llama 4 Scout (10M context - longest available)
  • Claude Opus 4.6 (200K context)
  • Gemini 3 Pro (1M+ context)

Code generation and review:

  • Claude Opus 4.6 (strongest at code with extended thinking)
  • GPT-5 (reliable structured outputs)
  • Llama 4 Maverick (open source alternative)

2. What are your cost constraints?

High volume, low margin: Use Gemini 3 Flash or GPT-5 mini for most requests. Route only complex queries to premium models.

Enterprise with budget: Use Claude Opus 4.6 or GPT-5 without much optimization. The quality difference often justifies the cost.

Self-hosted required: Llama 4 Scout runs on a single H100 with Int4 quantization - serious cost savings at scale with 10M context.

3. What are your latency requirements?

ModelTime to First TokenFull Response (500 tokens)
Gemini 3 Flash100-300ms0.5-1.5s
Claude Haiku 4.5150-350ms0.8-1.8s
GPT-5 mini200-400ms1-2s
GPT-5400-700ms2-4s
Claude Opus 4.6500-1000ms3-6s
Claude Opus 4.6 (extended thinking)2-10s5-30s

For real-time chat: Gemini 3 Flash, Haiku 4.5, or GPT-5 mini with streaming. For background processing: Quality matters more than speed - use extended thinking.

4. Do you need specific capabilities?

Function/tool calling:

  • GPT-5 has the most reliable structured outputs
  • Claude Opus 4.6 now has mature tool support
  • Llama 4 models support function calling natively

Vision (image/video understanding):

  • Llama 4 is natively multimodal (text, image, video)
  • Gemini 3 Pro handles long video well
  • Claude Opus 4.6 and GPT-5 both excellent for images

JSON mode / structured outputs:

  • GPT-5 with response_format is most reliable
  • Claude now supports structured outputs natively
  • Open source: use outlines or instructor libraries

Production architecture: multi-model routing

Most production platforms shouldn’t use a single model. Here’s the pattern we recommend:

┌─────────────────────────────────────────────────────────┐
│                    Request Router                        │
│  Analyzes: complexity, token count, latency requirements │
└───────────────────────┬─────────────────────────────────┘
                        │
        ┌───────────────┼───────────────┐
        ▼               ▼               ▼
   ┌─────────┐    ┌──────────┐    ┌──────────┐
   │ Simple  │    │ Standard │    │ Complex  │
   │ Flash/  │    │ GPT-5/   │    │ Opus 4.6 │
   │ Haiku   │    │ Sonnet   │    │ extended │
   └─────────┘    └──────────┘    └──────────┘
       80%            15%             5%
    of requests    of requests    of requests

Implementation example

function routeToModel(request: LLMRequest): ModelConfig {
  // Simple classification or extraction
  if (request.taskType === 'classify' || request.estimatedTokens < 500) {
    return { model: 'claude-haiku-4-5-20251101', maxTokens: 500 };
  }

  // Long context (over 200K tokens)
  if (request.estimatedTokens > 200000) {
    return { model: 'llama-4-scout', maxTokens: 8192 }; // 10M context
  }

  // Complex reasoning requiring extended thinking
  if (request.taskType === 'reasoning' || request.taskType === 'code') {
    return { model: 'claude-opus-4-5-20251101', maxTokens: 8192, extendedThinking: true };
  }

  // Default: balance of cost and quality
  return { model: 'claude-sonnet-4-5-20250929', maxTokens: 4096 };
}

This pattern typically reduces costs by 60-80% compared to using a premium model for everything.


Provider comparison: the details

OpenAI

Strengths:

  • Most reliable structured outputs and function calling
  • o3 reasoning models excel at complex multi-step tasks
  • Best developer tooling and documentation
  • Widest ecosystem of integrations

Weaknesses:

  • Rate limits can be restrictive at scale
  • Premium pricing on reasoning models
  • Occasional quality regressions between model versions

Best for: Startups that need to move fast, applications requiring reliable structured outputs.

Anthropic (Claude)

Strengths:

  • Opus 4.6 with extended thinking is best for complex reasoning
  • Strongest at code generation and review
  • Haiku 4.5 offers excellent speed at $1/$5 per 1M - best value for simple tasks in Claude ecosystem
  • Prompt caching saves up to 90%

Weaknesses:

  • Extended thinking adds latency (2-30s)
  • Smaller ecosystem than OpenAI

Best for: Enterprise applications, complex analysis, code-heavy workloads, agentic systems.

Google (Gemini)

Strengths:

  • Gemini 3 Flash is fast and affordable ($0.50/$3 per 1M)
  • Gemini 3 Pro handles 1M+ context well
  • Native multimodal including long video
  • 90% savings with context caching

Weaknesses:

  • API can still be less reliable than competitors
  • Reasoning models lag behind o3 and Opus 4.6

Best for: Cost-sensitive high-volume apps, long document processing, multimodal applications.

Open source (Llama 4, DeepSeek)

Strengths:

  • Llama 4 Scout: 10M context on single H100
  • Llama 4 is natively multimodal (text, image, video)
  • DeepSeek R1 offers competitive reasoning at low cost
  • Full control over data and infrastructure

Weaknesses:

  • Requires ML engineering expertise for self-hosting
  • GPU infrastructure costs and complexity
  • Llama 4 Behemoth (2T params) not yet released

Best for: High-volume applications, privacy-sensitive workloads, massive context requirements.


Cost optimization strategies

1. Prompt caching

Both OpenAI and Anthropic offer prompt caching for repeated system prompts. This can reduce costs by 50-90% for applications with consistent system instructions.

2. Batch processing

For non-real-time workloads, batch APIs offer 50% discounts:

  • OpenAI Batch API: 50% off, 24-hour completion
  • Anthropic Message Batches: 50% off, similar timing

3. Token budgets per request

Set hard limits on max_tokens and implement cost tracking per user/tenant:

const MONTHLY_BUDGET_PER_TENANT = 10.00; // $10/month

async function checkBudget(tenantId: string, estimatedCost: number) {
  const usage = await getMonthlyUsage(tenantId);
  if (usage + estimatedCost > MONTHLY_BUDGET_PER_TENANT) {
    throw new BudgetExceededError();
  }
}

4. Response caching

Cache LLM responses for identical queries. Even with embeddings-based similarity, you can cache 20-40% of requests in typical RAG applications.


Our current recommendations

For most B2B SaaS platforms:

  1. Primary model: Claude Opus 4.6 for quality
  2. Cost tier: Haiku 4.5 ($1/$5) or Gemini 3 Flash ($0.50/$3) for simple tasks
  3. Fallback: GPT-5 if Claude is down

For consumer applications (cost-sensitive):

  1. Primary: Gemini 3 Flash ($0.50/$3) for everything possible
  2. Premium tier: GPT-5 for complex requests
  3. Consider: Self-hosted Llama 4 Scout at scale

For enterprise (quality-first):

  1. Primary: Claude Opus 4.6 with extended thinking
  2. Long context: Llama 4 Scout (10M) or Gemini 3 Pro (1M)
  3. Reasoning: o3 for multi-step planning tasks

For privacy-critical / on-premises:

  1. Primary: Llama 4 Maverick (400B params, 1M context)
  2. Fast tier: Llama 4 Scout (runs on single H100)
  3. Consider: DeepSeek R1 for reasoning workloads

Getting started

Model selection is just one part of AI platform architecture. For help designing your LLM integration strategy:

View platform development service


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